You’ve probably come across plenty of CLEARSTEM acne supplement reviews online, from glowing success stories to frustrated users who saw little change.
But beyond the hype, it’s worth asking the real question: do the ingredients in CLEARSTEM actually help clear your skin, or could they cause unwanted side effects in some people?
In this review, we’ll break down what’s inside, what users are saying, and whether this popular supplement truly lives up to its promises of clear skin.
Clearstem Side Effects
- Fatigue or Drowsiness
→ From 5-HTP, which increases serotonin and may cause sleepiness or low energy in some users. - Hormonal Symptoms
→ DIM can shift estrogen metabolism and may cause:- Headaches
- Breakthrough bleeding
- Acne flare-ups (initially)
- Digestive Upset
→ From digestive enzymes or milk thistle, which may cause:- Bloating
- Gas
- Mild nausea
How Long Until You See Results?
The company claims results in 7–10 days and notes that foods that once triggered breakouts may no longer do so. However, it’s not meant to override deeper underlying issues.
Each bottle contains 90 capsules (3 per serving). Take with a meal to avoid nausea. If you weigh 125 lbs or less start with 2 capsules.
Interestingly, this is the first skin supplement we’ve seen with 5-HTP which is an ingredient more common in calming formulas. Because of this effect, CLEARSTEM suggests taking it in the evening if it makes you feel relaxed.
SEE MORE: Acnetame Supplement Review
Testimonials and Customer Reviews
The Clearstem hormonal acne supplement may not work for everyone as we've read bad reviews of numerous users not seeing results. We can understand their frustration considering you're supposed to see benefits quickly. Even after two months some had no luck.
More Clearstem supplements reviews can be found on Reddit and their website, but not on Amazon as it isn't sold there. If you're looking for a good acne supplement for hormonal breakouts on Amazon we
think you'll like Acne Tame.
Marissa
ClearSTEM review
I think I am going to be starting my third bottle soon and I don't think anything major has happened. Still have angry hormonal acne. It doesn't seem to be as effective as advertised. It is also so expensive with no
discounts from the company at all, which is very disappointing for a
potential product you would buy every month. Even the "subscribe and save" option is the exact same price on their website! And the Black Friday promo is even excluding this product.
Clearstem Ingredients
- 5-HTP
- Glutathione
- Vitamin B5
- DIM
- Vitamin A
- Dandelion Root
- Vitamin B6
- Vitamin B12
- Turmeric
- Protease
- Betaine hydrochloride
- Silicon dioxide
Where to Buy Clearstem skincare?
You can find Mind Body Skin on both Amazon and the CLEARSTEM website. They occasionally offer coupon codes, but there’s no discount for subscriptions.
One bottle costs $58, which is quite high for a 30-day supply.
We recommend trying Acnetame 30 count instead — it’s $19.99 and only requires one tablet daily, not three capsules.
Pros and Cons
What we find helpful is the founders of the company put together a masterclass called Clearstem ingredient checker which gives you knowledge about products that may be suitable for acne as well as skin care tips.
Pros:
-Contains some ingredients which help blemishes.
-Suitable for men & women.
-May help digestive issues.
Cons:
-Expensive for a 30 day supply.
-3 capsules daily.
-Could cause side effects like drowsiness.
Q&A
1. Does it cause breakouts?
Some people experience initial purging as their hormones and detox pathways adjust.
2. Is it safe for long-term use?
Yes, most ingredients are safe long-term, though it’s best to take breaks periodically and avoid combining it with other high-vitamin A or DIM supplements.
3. Can I take it with other acne supplements?
Not recommended — it may overlap ingredients which can throw off balance or cause side effects.
4. How long until I see results?
CLEARSTEM claims 7–10 days, but most users see clearer skin in 3–6 weeks with consistent use.
5. Should I take it in the morning or at night?
Either works, but because it contains 5-HTP, some find it makes them drowsy and prefer taking it in the evening.
SEE MORE: ALANI NU BALANCE HORMONAL ACNE REVIEW
CONCLUSION - Does CLEARSTEM Work?
We think Clearstem could work for some people. Our thoughts are that it's too expensive and there are ingredients in the stack which may not have an effect on acne such as 5-HTP and turmeric. Check out Acne Tame as it's a top rated acne pill on Amazon with proven results and great value.
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